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Solutions of Recombination Protein Process Filtration

Recombination Protein Process-Filtration-cbt.jpg

Recombinant human insulin is the world's first recombinant protein drug marketed for the treatment of type 1 and type 2 diabetes and has been used for more than 30 years. Development, insulin has now evolved from the first generation of animal-derived insulins to the fourth generation of long-acting insulin analogs. 


Recombinant human insulin is the world's first recombinant protein drug marketed for the treatment of type 1 and type 2 diabetes and has been used for more than 30 years. Development, insulin has now evolved from the first generation of animal-derived insulins to the fourth generation of long-acting insulin analogs. 


Recombinant protein drugs including:

1. Peptide hormones - recombinant human insulin, insulin analogs, recombinant human growth hormone and recombinant human follicle stimulating hormone, etc.

2. Cytokines -recombinant human follicle maturation hormone, recombinant human interferon  α、β、γ、 recombinant human granulocyte macrophage-stimulating factor, recombinant human erythropoietin, recombinant human interleukin 2,11, recombinant human epidermal growth factor. Recombinant human fibroblast growth factor, etc.

3. Recombinant enzymes - recombinant human urokinase progenitors, recombinant human α glucosidase preparations, etc., and others such as recombinant human bone formation Protein 2 and recombinant hirudin in various segments. 


The development of recombinant protein drugs is now in a stable phase and new technologies are important to extend the half-life of the drug in the body and change the form of delivery. Research into long-acting drugs is ongoing.



Solutions of Recombination Protein Process Filtration-cbt.jpg    

① Vent and Gas Filtration       

Safesure AFM -Hydrophobic PTFE

Aegivast ACE -Hydrophobic PTFE
Corevital APB -Hydrophobic PVDF



Buffer Filtration

Safetect?PME-PES
Purcise?PLE-Double Layers PES
Purcise?PAF-PES

Purcise?SLE-Double Layers PES

Purcise?SAF-Double Layers PES

Corevital?SMD-PVDF



③ Clarification Filtration

Roheap CSD

Greclary?CHV-Glass Fiber

Excesal?CHC-PP

Excesal?CHE-PP
Excesal?CHT-PP



④ Column / TFF Protection

Purcise PLE -Double Layer PES
Purcise PAF -PES
Safetect PME -PES
Corevital SAF -Double Layer PES

Purcise SLE -Double Layer PES

Purcise SPS -PES

Corevital SMD -PVDF



⑤ Concentration and Purification

Consieve?UET-PES



⑥ Sterile Filtration

Purcise?SLE-Double Layer PES

Purcise SPS -PES