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DPSHPC Sterilizing-Grade Liquid Filter

The DPSHPC series filter cartridge is composed of a unique PES filter membrane developed and improved by Cobetter. It can remove small particles, bacteria and endotoxins in the solution. The endotoxin removal efficiency in the physiological saline solution is more than 99%.

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Description Specifications Ordering Information

Description

Features

Modified PES
Fast flow rate and high throughput
pH1-14 tolerant
Can be pre-disinfected with NaOH
Good sterilization performance

Applications

Sterile and depyrogenation filtration for LVP and SVP
Sterile and depyrogenation filtration for antibiotic solution
Sterile and depyrogenation filtration for physiological saline and other solvents

Quality

100% Integrity testing in manufacturing
Each filter is fully traceable with unique serial number
Manufactured in a facility which adheres to ISO 9001:2015 Practices

Flow Rate Characteristics

Specifications

Materials of Construction

Membrane	Hydrophilic polyethersulfone (PES)
Support	Polypropylene (PP)
Core/Cage/End Caps	Polypropylene (PP)
End Cap Inserts	Polybutylene terephthalate (PBT)
Seal Material	Silicone / EPDM / Viton FEP/ PFA encapsulated O-rings

Operating Conditions

Max. Operating Temperature	80°C
Max.Operating Pressure	0.69 MPa@25°C 0.40 MPa@60°C 0.24 MPa@80°C
Max. Differential Pressure (Forward)	0.69 MPa@25°C 0.40 MPa@60°C 0.24 MPa@80°C
Max. Differential Pressure (Reverse)	0.30 MPa@25°C 0.10 MPa@80°C

Integrity Test Standards @10inch，20°C

Membrane Pore Size	Bubble Point	Diffusion Flow (Air)
0.22+0.22μm	≥ 0.32 MPa (water), Air test	≤ 28 ml/min @ 0.275 MPa (water)

Bacterial Retention

Model	Content
DPSHPC 0.22μm	Bacterial quantitative retention of 10? cfu/cm2 Brevundimonas diminuta (ATCC 19146) accordingto ASTM F838 methodology.

Sterilization

In-line steam sterilization	Up to 50 cycles (135 °C for 30 min and differential pressure < 30 kPa per cycle)
Autoclave	Up to 50 cycles (130 °C for 30 min per cycle)

Regulatory Compliance

Autoclaved filter effluent meets the USP<788> requirement of particulate matter in large volume injection.
Component materials meet the criteria for a "Non-fiber-releasing filter" as defined in 21 CFR 210.3(b)(6).
Aqueous extraction from a cartridge contains less than 0.25EU/ml as determined by Limulus Amebocyte Lysate (LAL), meeting requirements of USP<85>.
Meet the requirement of USP <87> In Vitro Cytotoxicity Test.
Component materials meet the requirements of the current USP<88> for plastic class VI-121°C.
All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182.
Based on the current information from our suppliers, all component materials used in the manufacture of this product are animal-free.

End Cap

Ordering Information

Outer Diameter	Type	Membrane Pore Size	End Cap	Nominal Length	Seal Material	Industry
69mm	DPSHPC	2222 0.22+0.22μm	DOE Double Open End	05 5 inch	S Silicone	P
			HTF 222/Fin	10 10 inch	E EPDM
			HSF 226/Fin	20 20 inch	V Viton
			HTCG 222/Flat	30 30 inch	P FEP/PFA encapsulated O-rings
			HSCG 226/Flat	40 40 inch

* Example：DPSHPC2222DOE05SP (DPSHSL，0.22+0.22μm，Double open end，5 inch，Silicone，Pharmaceutical)

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